[U-13C]palmitic acid

[U-13C]palmitic acid is a stable isotope-labeled form of palmitic acid, a 16-carbon saturated fatty acid, where all 16 carbon atoms are replaced with carbon-13 (13C). It is widely utilized as a metabolic tracer in clinical research and diagnostic studies to investigate lipid kinetics, fatty acid oxidation, lipolysis, and ketogenesis. When administered orally or intravenously, the tracer's metabolic fate can be monitored by measuring the enrichment of 13C in plasma free fatty acids, triglycerides, 3-hydroxybutyrate, and expired breath carbon dioxide (13CO2) using mass spectrometry. This allows for the quantitative assessment of mitochondrial beta-oxidation, chylomicron triacylglycerol concentrations, and the diagnosis of fatty acid oxidation defects.

Other names

13C16-palmitate13C16-palmitic acidU-13C-palmitateU13C-palmitateU 13C-palmitateU-13C-palmitic acidU13C-palmitic acidU 13C-palmitic acid[U-13C16]palmitate[U-13C16]palmitic acid[U-13C]palmitateuniformly 13-carbon labeled palmitateuniformly13-carbon labeled palmitateuniformly-13-carbon labeled palmitateuniformly labeled [U-13C]palmitate